The FDA initiates class I drug recalls when products have the reasonable possibility of causing serious adverse health consequences or death. According to a new study, about two-thirds of FDA-recalled dietary supplements analyzed still contained banned drugs at least six months after being recalled.
Researchers are decoding the structure of the large ribosomal subunit of the mitochondria at an atomic level, thereby providing insight into the molecular architecture of this ribosome with implications for a better understanding of the mode of action of antibiotics.
A new method allows chemists to measure how fast a small molecule binds to and unbinds from a protein without modifying or labeling either molecule. Researchers could use the approach to rank potential drug candidates by their ability to form stable complexes with a target protein.
When researchers invented the field of biological accelerator mass spectrometry in the late 1980s, the process of preparing the samples was time-consuming and cumbersome. Now, with the aid of a new sample preparation method that accommodates liquid samples and bypasses the graphitization process, scientists can prepare and analyze samples in minutes– instead of days.
A new technique makes it possible to quickly detect the presence of drugs or monitor certain medical conditions using only a single drop of blood or urine, representing a potential tool for clinicians and law enforcement.
As the UK forms a new crime unit designed to fight food fraud— in response to an uproar last year over horse meat being passed off as beef— scientists from Germany are reporting a technique for detecting meat adulteration.
Researchers have succeeded in observing the "forbidden" infrared spectrum of a charged molecule for the first time. These weak spectra offer perspectives for extremely precise measurements of molecular properties and may also contribute to the development of molecular clocks and quantum technology.
An ultra-sensitive biosensor made from the wonder material graphene has been used to detect molecules that indicate an increased risk of developing cancer. The biosensor has been shown to be more than five times more sensitive than bioassay tests currently in use, and was able to provide results in a matter of minutes.
A student who develops new analytical methods using liquid chromatography and gas phase chemistry in mass spectrometry to characterize a group of pharmaceuticals known to be highly heterogeneous has been awarded the 2014-15 Global Fellowship Award from the U.S. Pharmacopeial Convention.
Although in modern societies fermented beverages are associated with socializing, celebration and ritual, in ancient times they were also important sources of essential nutrients and potable water. In Mesoamerica, pulque— an alcoholic beverage produced from the fermented sap of several species of maguey plants— is hypothesized to have been used as a dietary supplement.
A new research platform uses a laser to measure the nanomechanical properties of tiny structures undergoing stress and heating, an approach likely to yield insights to improve designs for microelectronics and batteries.
Multilayer-coated mirrors, if used as focusing optics in the soft gamma-ray photon energy range, can enable and advance a range of scientific and technological applications. Researchers have demonstrated that very short-period multilayer coatings deposited on super-polished substrates operate efficiently as reflective optics above 0.6 MeV, nearly a factor of two higher than the previous record at 384 keV, set last year by this same group.
Dubbed a “cousin of graphene,” germanene— which is made up of just a single layer of germanium atoms— is expected to exhibit impressive electrical and optical properties and could be widely integrated across the electronics industry in the future.
The timing of food intake in the early phase of TB treatment could have a negative impact on the effectiveness of TB treatment. A new study suggests that eating food just before taking a TB drug could reduce the effectiveness of the medicine.
As dwindling populations of monarch butterflies prepared for their annual migration, two undergraduate students spent their summer trying to more deeply understand the plants upon which they rely. They hope their research will help future work by deepening the understanding of evolutionary relationships developed between milkweed and butterflies, beetles, wasps and other insects.
Innova Biosciences has launched InnovaGOLD, a range of ultra-high-quality gold nanoparticles that have demonstrated improved sensitivity, stability and reproducibility in immunoassays compared to other commercially available gold colloids.
Shimadzu Scientific Instruments has added to its integrated liquid chromatography systems line with the Prominence-i and Nexera-i. Combining enhanced functionality, an intuitive operating environment and full automation, the series provides excellent performance and a more efficient workflow for conventional to ultra-high-speed analysis.
Wyatt Technology’s DynaPro Plate Reader II can run automated high-throughput screening-dynamic light scattering analyses to characterize protein-protein interactions in standard microwell plates, under multiple conditions in a significantly reduced time frame, making DLS a viable option for stability-indicating parameter (SIP) screening.
Restek has developed a new certified reference material (CRM) of four PAHs—benz[a]anthracene, benzo[a]pyrene, benzo[b]fluoranthene, and chrysene—designed for greater convenience, longer shelf life and increased long-term accuracy.
Practichem has added to its Chromponents line with the BioD3, a compact LED-based UV and conductivity detector, and FluidSwitch, a line of biocompatible rotary valves. Chromponents is a series of modules designed for easy configuration.
Phenomenex has added Phenova Certified Reference Materials (CRMs), a line of ISO/IEC 17025- and ISO Guide 34-compliant standards for the calibration of analytical equipment and quantitation of analytical measurements for environmental testing.