Because of the high cost of HPLC columns, there are numerous ways to find out which column(s) might best be of use for an intended but new separation. If some of the components are known, then the literature or manufacturers’ websites can be consulted. This might take some time, but the research of others can save both time and money in your own work.
Pre-formulated buffers for pH gradient have greatly simplified the development of ion exchange chromatography (IEX) of monoclonal antibodies (mAbs). Three features make this simplification possible.
Soft ionization remains a relatively underused technique for GCMS, despite its ability to provide improved confidence in the identification of a range of challenging analytes. But there is now a new approach that makes it possible to lower the energy of electron ionization to achieve soft ionization, without the disadvantages with which it has historically been associated.
Mass spectrometry (MS) is the workhorse of analytical chemistry. It performs the analysis of the sample, making MS equipment an essential part of the analytical instrumentation market. A recent shift in the laboratory landscape, however, is forcing a change in the size and functionality of mass spec equipment.
Researchers at Purdue Univ. have pioneered a separation technique that can be used in everything from homeland security and law enforcement to drug discovery and biomedical applications. The technique, called slug flow microextraction, makes it possible to quickly detect the presence of drugs or monitor certain medical conditions using only a single drop of blood or urine.
More detailed and comprehensive data analysis through MS solutions is revolutionizing the biological and clinical research industry.
New technologies are making it easier, faster and more reliable to detect explosives or highly energetic materials before they can be used.
On-site hydrogen generators are safe, reduce run times and improve gas chromatography results.
High-quality filtration in sample and mobile phase separation is crucial to guarantee reproducible HPLC and UHPLC data.
New diamond-based HPLC technology enables complex separations and regeneration in drug research.
New UHPLC system combines ruggedness, flexibility and serviceability, along with substantially improved performance.
A combination of microfluidics and electronic integration results in simpler sample analysis.
Users are turning to increasingly simple chromatography data systems to handle increasingly complex processes.
Capillary electrophoresis has emerged as a powerful tool in the fight against adulterated food and beverage.
The capabilities of ion chromatography are essential as hexavalent chromium limits plunge ever lower in the attempt to ensure safe drinking water for all.
A decades-old theory and a new super-localization microscopy method have teamed to advance the efficiency of ion chromatography in drug discovery applications.
Global researchers are working together to develop methodologies to identify pesiticides in food with triple quadrupole chromatography systems.
Advanced, sensitive liquid chromatography techniques have helped trace the evolution of alcohol.
Chromatography systems’ modularity is increasing accessibility of the technique from a specialized skill to a mainstay for research scientists.