Despite the popularity of HPLC, it isn’t always clear which grade of solvent should be selected when performing HPLC analysis for gradient applications. Using an incorrect solvent can lead to unstable baselines, ghost peaks and perceived product quality issues. To ensure the most reliable results from HPLC analysis, it is important to choose the correct solvent grade.
Updates to the allowed limits of HPLC and GC parameters enable higher-speed analysis of USP methods than ever before.
Dual-column gas chromatography meets the needs of the environmental testing industry by providing fast, accurate separation of multiple halogenated compound classes.
Multiple gas chromatography methods are being deployed to monitor a suite of fracking-related contaminants that may be present in drinking water.
Accelerator mass spectrometry (AMS) is an analytical technique for measuring isotope ratios with high selectivity, sensitivity and precision. Initially developed more than 75 years ago by Robert Cornog and Luis Alvarez at the Univ. of California, Berkeley, there are now more than 110 AMS systems in 28 countries around the world, mostly at government and university labs, but a few at private companies as well.
As illustrated by experimental results, imaging in high-magnification mode is faster and results in more spectral and spatial detail.
Near-infrared spectroscopy reduces the amount of time and work needed to test sustained-release tablets, and ensures nondestructive, reliable analysis.
Because of the high cost of HPLC columns, there are numerous ways to find out which column(s) might best be of use for an intended but new separation. If some of the components are known, then the literature or manufacturers’ websites can be consulted. This might take some time, but the research of others can save both time and money in your own work.
Pre-formulated buffers for pH gradient have greatly simplified the development of ion exchange chromatography (IEX) of monoclonal antibodies (mAbs). Three features make this simplification possible.
Soft ionization remains a relatively underused technique for GCMS, despite its ability to provide improved confidence in the identification of a range of challenging analytes. But there is now a new approach that makes it possible to lower the energy of electron ionization to achieve soft ionization, without the disadvantages with which it has historically been associated.
Mass spectrometry (MS) is the workhorse of analytical chemistry. It performs the analysis of the sample, making MS equipment an essential part of the analytical instrumentation market. A recent shift in the laboratory landscape, however, is forcing a change in the size and functionality of mass spec equipment.
Researchers at Purdue Univ. have pioneered a separation technique that can be used in everything from homeland security and law enforcement to drug discovery and biomedical applications. The technique, called slug flow microextraction, makes it possible to quickly detect the presence of drugs or monitor certain medical conditions using only a single drop of blood or urine.
More detailed and comprehensive data analysis through MS solutions is revolutionizing the biological and clinical research industry.
New technologies are making it easier, faster and more reliable to detect explosives or highly energetic materials before they can be used.
On-site hydrogen generators are safe, reduce run times and improve gas chromatography results.
High-quality filtration in sample and mobile phase separation is crucial to guarantee reproducible HPLC and UHPLC data.
New diamond-based HPLC technology enables complex separations and regeneration in drug research.
New UHPLC system combines ruggedness, flexibility and serviceability, along with substantially improved performance.
A combination of microfluidics and electronic integration results in simpler sample analysis.