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Lab Daily

Using TLC to Choose an HPLC Column

December 10, 2014 11:55 am | by Fred Rabel, Owner, ChromHELP, LLC, Woodbury, N.J.

Because of the high cost of HPLC columns, there are numerous ways to find out which column(s) might best be of use for an intended but new separation. If some of the components are known, then the literature or manufacturers’ websites can be consulted. This might take some time, but the research of others can save both time and money in your own work.

pH Gradient Speeds Separation of Antibodies

December 10, 2014 11:47 am | by Ken Cook, Frank Steiner, Mauro De Pra, Thermo Fisher Scientific, Inc.

Pre-formulated buffers for pH gradient have greatly simplified the development of ion exchange chromatography (IEX) of monoclonal antibodies (mAbs). Three features make this simplification possible.

Soft Ionization Drives Future GCMS Technology

December 10, 2014 11:37 am | by Laura McGregor, Nick Bukowski and David Barden, Markes International, UK

Soft ionization remains a relatively underused technique for GCMS, despite its ability to provide improved confidence in the identification of a range of challenging analytes. But there is now a new approach that makes it possible to lower the energy of electron ionization to achieve soft ionization, without the disadvantages with which it has historically been associated.

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Higher Performance, Smaller Sizes Define Future Mass Spec

December 10, 2014 11:23 am | by Sarah Smith, Global Market Manager, Analytical, Bal Seal Engineering Inc., Foothill Ranch, Calif.

Mass spectrometry (MS) is the workhorse of analytical chemistry. It performs the analysis of the sample, making MS equipment an essential part of the analytical instrumentation market. A recent shift in the laboratory landscape, however, is forcing a change in the size and functionality of mass spec equipment.

What a Single Drop of Blood Can Reveal

December 5, 2014 9:29 am | by Michelle Taylor, Editor-in-Chief

Researchers at Purdue Univ. have pioneered a separation technique that can be used in everything from homeland security and law enforcement to drug discovery and biomedical applications. The technique, called slug flow microextraction, makes it possible to quickly detect the presence of drugs or monitor certain medical conditions using only a single drop of blood or urine.

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MS Innovations Advance Bio, Clinical Research

September 4, 2014 12:37 pm | by Michelle Taylor, Editor

More detailed and comprehensive data analysis through MS solutions is revolutionizing the biological and clinical research industry.                                                 

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TLC Detection of Explosives

September 4, 2014 12:28 pm | by Tim Studt, Editorial Director

New technologies are making it easier, faster and more reliable to detect explosives or highly energetic materials before they can be used.

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Hydrogen: Minimizing Risks, Maximizing Results

September 4, 2014 12:21 pm | by arry Moulthrop, Vice President of Hydrogen Systems, Proton OnSite

On-site hydrogen generators are safe, reduce run times and improve gas chromatography results.                                                 

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Proper Sample Prep Ensures HPLC Success

September 4, 2014 12:10 pm | by Vivek Joshi, Principal Research Scientist, EMD Millipore

High-quality filtration in sample and mobile phase separation is crucial to guarantee reproducible HPLC and UHPLC data.                                                                 

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Understanding Protein Compounds in Drug Discovery

September 4, 2014 12:06 pm | by Diamond Analytics

New diamond-based HPLC technology enables complex separations and regeneration in drug research.                                                                    

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Enhanced Throughput, Resolution and Peak Capacity

September 4, 2014 11:53 am | by Tim Studt, Editorial Director

New UHPLC system combines ruggedness, flexibility and serviceability, along with substantially improved performance.                                                              

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Game-changing Liquid Chromatography

June 11, 2014 9:33 am | by Tim Studt, Editorial Director

A combination of microfluidics and electronic integration results in simpler sample analysis.                                                      

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Simple Software for an Advanced Industry

June 11, 2014 9:24 am | by Michelle Taylor, Editor

Users are turning to increasingly simple chromatography data systems to handle increasingly complex processes.                                                                  

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CE Tells You What’s Really in Your Food

June 11, 2014 9:17 am | by Vadim Okun, Senior R&D Scientist, Lumex Instruments, Canada

Capillary electrophoresis has emerged as a powerful tool in the fight against adulterated food and beverage.                                                           

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Ensuring Toxic-free Drinking Water

June 10, 2014 5:07 pm | by Michelle Taylor, Editor

The capabilities of ion chromatography are essential as hexavalent chromium limits plunge ever lower in the attempt to ensure safe drinking water for all.                                                                    

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Lending Ion Chromatography a ‘Hand’

June 10, 2014 4:59 pm | by Skip Derra, Contributing Writer

A decades-old theory and a new super-localization microscopy method have teamed to advance the efficiency of ion chromatography in drug discovery applications.                                              

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Collaborative Chromatography Identifies Multiple Residue Pesticides

February 10, 2014 12:58 pm | by Tim Studt, Editorial Director

Global researchers are working together to develop methodologies to identify pesiticides in food with triple quadrupole chromatography systems.                                                     

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On the Trail of Ancient Wines and Beers

February 10, 2014 12:46 pm | by Skip Derra, Arizona State Univ.

Advanced, sensitive liquid chromatography techniques have helped trace the evolution of alcohol.                                                                   

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How Design Innovations are Revolutionizing Chromatography

February 10, 2014 12:41 pm | by Laura Moriarty, Bio-Rad Laboratories, and Mary Napier and Annette Summers, GeneCom Group

Chromatography systems’ modularity is increasing accessibility of the technique from a specialized skill to a mainstay for research scientists.                                      

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Water, Ice or Neat? GC Evaluates Whisky Drinks

February 10, 2014 12:34 pm | by David Scott, PerkinElmer, Inc.

Gas chromatography can be successfully used in the aroma study of potable spirits, such as whisky.                                                                 

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