Liquid Chromatography
Subscribe to Liquid Chromatography

The Lead

Game-changing Liquid Chromatography

June 11, 2014 9:33 am | by Tim Studt, Editorial Director | Articles | Comments

A combination of microfluidics and electronic integration results in simpler sample analysis.

LC Detector Handles Semi-Volatile Compounds

September 4, 2013 10:06 am | by Thermo Fisher Scientific, Inc. | Product Releases | Comments

Thermo Fisher Scientific’s Corona Veo is an advanced charged aerosol detector (CAD) for liquid...

Technology Speeds Drying of HPLC Samples

September 4, 2013 9:54 am | by Genevac Ltd. | Product Releases | Comments

Genevac’s HT Series II Evaporator using the Fast Lyophilisation, or LyoSpeed process enables...

Triple Quadrupole Mass Spectrometers Offer High Performance

September 4, 2013 9:53 am | by Bruker Corp. | Product Releases | Comments

Bruker’s EVOQ series of LC-triple quadrupole mass spectrometers includes the high-performance...

View Sample

FREE Email Newsletter

Imaging Analysis Ensures HPLC Column Performance

February 8, 2013 11:53 am | by Particulate Systems, Norcross, Ga. | Articles | Comments

If there was a method for packing material manufacturers to specify shape characteristics and for column manufacturers to inspect incoming materials against those specifications, manufacturing HPLC columns would become more predictable, less costly and exhibit consistent performance. Recent advancements in image analysis could provide the answer.

UHPLC MS/MS Method Rids Water of Contaminants

February 8, 2013 11:41 am | by Tarun Anumol, Sylvain Merel and Shane Snyder, Department of Chemical and Environmental Engineering, BIO5 Institute, Univ. of Arizona, Tucson, Ariz. | Articles | Comments

This article describes a method for the rapid and sensitive detection of 36 CEC analytes in less than 20 minutes per sample. This UHPLC MS/MS method was developed on an Agilent 1290 Infinity LC system coupled to an Agilent 6460 Triple Quadrupole LCMS system using both positive and negative electrospray ionization.

New C18 Columns Expand Methods Development Toolbox

February 8, 2013 11:22 am | by Derek Jensen, Hamilton Co., and Carol Preisig and Annette Summers, Consultants, GeneCom Group | Articles | Comments

The flexibility to perform separations without pH, temperature or mobile phase restrictions arms chromatographers with powerful tools for tackling tough separations. The right combination of stationary and mobile phase is critical for generating the well-defined, sharp peaks that allow shorter run times.


Chiral Separation Gets an MS-Based Upgrade

February 8, 2013 11:11 am | by Waters Corp., Milford, Mass. | Articles | Comments

A multitude of performance factors including dense gas CO2, small particle columns and mass spectrometry with UV detection are speeding up chiral separation methods development. Chirality plays a critical role in drug efficacy because enantiomers may have vastly different biological, pharmacological and toxicological properties.

Nickel-Clad Tubing Suited for HPLC, UHPLC

February 7, 2013 12:33 pm | Product Releases | Comments

VICI Valco’s nickel-clad tubing is available with fused silica (FS) tubing, PEEK tubing band polyimide-coated fused silica tubing. These selections make the nickel-clad tubing suited for HPLC and UHPLC use.

2013 Catalog Showcases Chromatography, Spectroscopy Offerings

February 7, 2013 12:26 pm | by Agilent Technologies Inc. | Product Releases | Comments

Agilent Technologies’ 2013 Essential Chromatography and Spectroscopy Catalog is divided into five sections to help the reader easily navigate the company’s growing portfolio, which includes general chromatography, sample preparation, GC and GCMS, LC and LCMS and spectroscopy. This edition of the catalog contains CrossLab products for use with other manufacturers’ instruments. It also includes details about electrochemistry meters and supplies, Captiva syringe filters, Ultra Inert and application-specific GC columns, LC biomolecule and Poroshell 120 columns and OneNeb nebulizer for ICP-OES and MP-AES.

CRMs Suited for Testing by LCMS, GCMS

February 7, 2013 12:22 pm | by Cerilliant Corp. | Product Releases | Comments

Cerilliant offers Certified Spiking Solutions of nicotine metabolites norcotinine and trans-3-hydroxycotinine, as well as nicotine nitrosamines NNN, NNK and NAB at concentrations of 1.0 mg/mL in methanol for each solution standard. These certified reference solutions can be used as Snap-N-Spike starting materials in the laboratory’s matrix of choice for preparation of calibrators and controls in nicotine testing and other clinical or diagnostic applications by LCMS or GCMS.

Software Solution Tailored to Small Chromatography Labs

February 7, 2013 12:17 pm | by Agilent Technologies | News | Comments

Agilent Technologies’ OpenLAB Data Store with Lab Applications is an out-of-the-box solution for smaller laboratories that provides secure central storage of the data produced by the proprietary OpenLAB chromatography data systems. The software is designed to streamline the management of laboratory operations, assets and regulatory compliance.


MS Lab Furniture Reduces Noise, Vibration

February 7, 2013 12:11 pm | by IonBench | News | Comments

IonBench’s furniture offerings are dedicated to bringing quiet, vibration-free solutions to mass spectroscopy and liquid chromatography. The MS Bench incorporates a soundproofing solution with anti-vibration features in a solidly-built bench that can reduce system footprint by 30%.

HPLC Columns Offer 3 Micron Particles

February 7, 2013 12:08 pm | by Thermo Fisher Scientific, Inc. | Product Releases | Comments

Thermo Fisher Scientific’s Syncronis HPLC columns are available with 3 mm particle size. This particle size complements the existing 1.7 and 5 µm particle sizes.

LC Columns Designed for Protein Separation

February 7, 2013 12:05 pm | by Protea Biosciences Group, Inc. | Product Releases | Comments

Protea Biosciences Group’s Amplus wide-pore core shell HPLC columns are a line of liquid chromatography columns specifically designed for intact proteins analysis. This family of HPLC silica-based columns employs core shell technology combined with a specific porosity designed to facilitate proteins separation, including those with high molecular weight.

Online Column Selector Simplifies the Process

February 7, 2013 12:03 pm | by IDEX Health & Science LLC | Product Releases | Comments

Isolation Technologies’ new, interactive online tool shows instrument manufacturers and laboratory scientists a broad range of empty column hardware and accessories available from IDEX Health & Science. The interactive brochure as a enables the user to see the most popular in-stock hardware and select by specification.

HPLC, UHPLC Columns Specifically Suited for Bioanalysis

February 7, 2013 11:59 am | by Fortis Technologies | Product Releases | Comments

Fortis Technologies is expanding its current range of liquid chromatography products with the launch of its BIO HPLC and UHPLC Columns. Centered around a 300A silica matrix, the phases are designed specifically for bioanalysis of peptides and proteins, where a larger pore size is required to provide retention and selectivity.


HPLC Columns Improve Herbicide Separations

December 11, 2012 2:03 pm | by Thermo Fisher Scientific, Inc. | Product Releases | Comments

Thermo Fisher Scientific’s Acclaim Trinity Q1 HPLC columns are designed to facilitate high-resolution and high-throughput trace analysis of the herbicides diquat and paraquat in plants by LCMS.

Integrated Titration, IC System Streamlines Workflow

December 11, 2012 1:25 pm | by Thermo Fisher Scientific, Inc. | Product Releases | Comments

Thermo Fisher Scientific and METTLER TOLEDO have collaborated to provide a combined Titration/Ion Chromatography (IC) system designed to provide a fast, accurate and integrated solution for fully automated water analysis for laboratories testing the quality of drinking, surface or ground water.

System Offers UHPLC Flexibility

September 5, 2012 11:19 am | by Thermo Fisher Scientific, Inc. | Product Releases | Comments

Thermo Fisher Scientific’s UltiMate 3000 XRS UHPLC system offers UHPLC capabilities in solvent delivery and sample handling with a range of detector options for high-throughput laboratories. 

Column Toolbox Ensures Correct Selections

September 5, 2012 11:17 am | by Restek Corp. | Product Releases | Comments

Restek’s USLC column set represents a range of reversed phase selectivity with just four stationary phases: aqueous C18, IBD, biphenyl, and PFP propyl. 

UHPLC System Designed Specifically for Proteomics

September 5, 2012 11:00 am | by Bruker Daltonics | Product Releases | Comments

Bruker’s nano-Advance UHPLC system for capillary and nano-flow LCMS applications further enhanced the company’s integrated solutions for proteomics. 

Integrated Digestion Platform Simplifies Sample Preparation

June 1, 2012 8:33 am | Product Releases | Comments

In partnership with Perfinity Biosciences, Shimadzu Scientific Instruments has released the Perfinity Integrated Digestion Platform (IDP).

Heating Block System Improves Stability Studies

June 1, 2012 8:33 am | Product Releases | Comments

Asynt has supplied a European Contract Research Organization (CRO) with a custom heating block system to assist chemists analyzing the thermal stability of multiple samples being prepared for its commercial compound libraries.

Integrated LC-DAD System Supports HPLC, UHPLC

June 1, 2012 8:33 am | Product Releases | Comments

Agilent Technologies' 1220 Infinity LC system with DAD brings UHPLC analytical power with diode-array detection to users who do not need the flexibility of a modular system, but still require the highest quality at a low price.

Growth of UHPLC-Enabled Technologies

May 31, 2012 7:28 am | Articles | Comments

Development of new ultra-high performance liquid chromatography and mass spectrometry technologies has seen dramatic growth in the past decade—and look for even more in the near future.

Breaking the 20,000 PSI Barrier

February 7, 2012 5:43 am | Articles | Comments

 LC pump engineers have undertaken the formidable task of reaching 20,000 psi and above, rethinking and possibly revolutionizing the pump design.

Vials Certified for High-Sensitivity LCMS MS

December 5, 2011 12:18 pm | Product Releases | Comments

Waters’ TruView LCMS Certified Vials, a line of low-adsorption sample vials, are certified for LCMS/MS analyses where analyte concentrations are on the order of ng/mL or pg/mL and where analytical sensitivity and accuracy are critical.

Web-Based Calculator Simplifies HPLC

December 5, 2011 12:15 pm | Product Releases | Comments

Thermo Fisher Scientific provides web-based chromatography assistance to chromatographers looking to optimize methods with the latest column technologies with the HPLC Method Development Calculator.

You may login with either your assigned username or your e-mail address.
The password field is case sensitive.