Liquid Chromatography
Imaging Analysis Ensures HPLC Column Performance
February 8, 2013 11:53 am | by Particulate Systems, Norcross, Ga. | Articles | CommentsIf there was a method for packing material manufacturers to specify shape characteristics and for column manufacturers to inspect incoming materials against those specifications, manufacturing HPLC columns would become more predictable, less costly and exhibit consistent performance. Recent advancements in image analysis could provide the answer.
UHPLC MS/MS Method Rids Water of Contaminants
February 8, 2013 11:41 am | by Tarun Anumol, Sylvain Merel and Shane Snyder, Department of Chemical and Environmental Engineering, BIO5 Institute, Univ. of Arizona, Tucson, Ariz. | Articles | CommentsThis article describes a method for the rapid and sensitive detection of 36 CEC analytes in less than 20 minutes per sample. This UHPLC MS/MS method was developed on an Agilent 1290 Infinity LC system coupled to an Agilent 6460 Triple Quadrupole LCMS system using both positive and negative electrospray ionization.
New C18 Columns Expand Methods Development Toolbox
February 8, 2013 11:22 am | by Derek Jensen, Hamilton Co., and Carol Preisig and Annette Summers, Consultants, GeneCom Group | Articles | CommentsThe flexibility to perform separations without pH, temperature or mobile phase restrictions arms chromatographers with powerful tools for tackling tough separations. The right combination of stationary and mobile phase is critical for generating the well-defined, sharp peaks that allow shorter run times.
Chiral Separation Gets an MS-Based Upgrade
February 8, 2013 11:11 am | by Waters Corp., Milford, Mass. | Articles | CommentsA multitude of performance factors including dense gas CO2, small particle columns and mass spectrometry with UV detection are speeding up chiral separation methods development. Chirality plays a critical role in drug efficacy because enantiomers may have vastly different biological, pharmacological and toxicological properties.
Nickel-Clad Tubing Suited for HPLC, UHPLC
February 7, 2013 12:33 pm | Product Releases | CommentsVICI Valco’s nickel-clad tubing is available with fused silica (FS) tubing, PEEK tubing band polyimide-coated fused silica tubing. These selections make the nickel-clad tubing suited for HPLC and UHPLC use.
2013 Catalog Showcases Chromatography, Spectroscopy Offerings
February 7, 2013 12:26 pm | by Agilent Technologies Inc. | Product Releases | CommentsAgilent Technologies’ 2013 Essential Chromatography and Spectroscopy Catalog is divided into five sections to help the reader easily navigate the company’s growing portfolio, which includes general chromatography, sample preparation, GC and GCMS, LC and LCMS and spectroscopy. This edition of the catalog contains CrossLab products for use with other manufacturers’ instruments. It also includes details about electrochemistry meters and supplies, Captiva syringe filters, Ultra Inert and application-specific GC columns, LC biomolecule and Poroshell 120 columns and OneNeb nebulizer for ICP-OES and MP-AES.
CRMs Suited for Testing by LCMS, GCMS
February 7, 2013 12:22 pm | by Cerilliant Corp. | Product Releases | CommentsCerilliant offers Certified Spiking Solutions of nicotine metabolites norcotinine and trans-3-hydroxycotinine, as well as nicotine nitrosamines NNN, NNK and NAB at concentrations of 1.0 mg/mL in methanol for each solution standard. These certified reference solutions can be used as Snap-N-Spike starting materials in the laboratory’s matrix of choice for preparation of calibrators and controls in nicotine testing and other clinical or diagnostic applications by LCMS or GCMS.
Software Solution Tailored to Small Chromatography Labs
February 7, 2013 12:17 pm | by Agilent Technologies | News | CommentsAgilent Technologies’ OpenLAB Data Store with Lab Applications is an out-of-the-box solution for smaller laboratories that provides secure central storage of the data produced by the proprietary OpenLAB chromatography data systems. The software is designed to streamline the management of laboratory operations, assets and regulatory compliance.
MS Lab Furniture Reduces Noise, Vibration
February 7, 2013 12:11 pm | by IonBench | News | CommentsIonBench’s furniture offerings are dedicated to bringing quiet, vibration-free solutions to mass spectroscopy and liquid chromatography. The MS Bench incorporates a soundproofing solution with anti-vibration features in a solidly-built bench that can reduce system footprint by 30%.
HPLC Columns Offer 3 Micron Particles
February 7, 2013 12:08 pm | by Thermo Fisher Scientific, Inc. | Product Releases | CommentsThermo Fisher Scientific’s Syncronis HPLC columns are available with 3 mm particle size. This particle size complements the existing 1.7 and 5 µm particle sizes.
LC Columns Designed for Protein Separation
February 7, 2013 12:05 pm | by Protea Biosciences Group, Inc. | Product Releases | CommentsProtea Biosciences Group’s Amplus wide-pore core shell HPLC columns are a line of liquid chromatography columns specifically designed for intact proteins analysis. This family of HPLC silica-based columns employs core shell technology combined with a specific porosity designed to facilitate proteins separation, including those with high molecular weight.
Online Column Selector Simplifies the Process
February 7, 2013 12:03 pm | by IDEX Health & Science LLC | Product Releases | CommentsIsolation Technologies’ new, interactive online tool shows instrument manufacturers and laboratory scientists a broad range of empty column hardware and accessories available from IDEX Health & Science. The interactive brochure as a enables the user to see the most popular in-stock hardware and select by specification.
HPLC, UHPLC Columns Specifically Suited for Bioanalysis
February 7, 2013 11:59 am | by Fortis Technologies | Product Releases | CommentsFortis Technologies is expanding its current range of liquid chromatography products with the launch of its BIO HPLC and UHPLC Columns. Centered around a 300A silica matrix, the phases are designed specifically for bioanalysis of peptides and proteins, where a larger pore size is required to provide retention and selectivity.
HPLC Columns Improve Herbicide Separations
December 11, 2012 2:03 pm | by Thermo Fisher Scientific, Inc. | Product Releases | CommentsThermo Fisher Scientific’s Acclaim Trinity Q1 HPLC columns are designed to facilitate high-resolution and high-throughput trace analysis of the herbicides diquat and paraquat in plants by LCMS.
Integrated Titration, IC System Streamlines Workflow
December 11, 2012 1:25 pm | by Thermo Fisher Scientific, Inc. | Product Releases | CommentsThermo Fisher Scientific and METTLER TOLEDO have collaborated to provide a combined Titration/Ion Chromatography (IC) system designed to provide a fast, accurate and integrated solution for fully automated water analysis for laboratories testing the quality of drinking, surface or ground water.
System Offers UHPLC Flexibility
September 5, 2012 11:19 am | by Thermo Fisher Scientific, Inc. | Product Releases | CommentsThermo Fisher Scientific’s UltiMate 3000 XRS UHPLC system offers UHPLC capabilities in solvent delivery and sample handling with a range of detector options for high-throughput laboratories.
Column Toolbox Ensures Correct Selections
September 5, 2012 11:17 am | by Restek Corp. | Product Releases | CommentsRestek’s USLC column set represents a range of reversed phase selectivity with just four stationary phases: aqueous C18, IBD, biphenyl, and PFP propyl.
UHPLC System Designed Specifically for Proteomics
September 5, 2012 11:00 am | by Bruker Daltonics | Product Releases | CommentsBruker’s nano-Advance UHPLC system for capillary and nano-flow LCMS applications further enhanced the company’s integrated solutions for proteomics.
Integrated Digestion Platform Simplifies Sample Preparation
June 1, 2012 8:33 am | Product Releases | CommentsIn partnership with Perfinity Biosciences, Shimadzu Scientific Instruments has released the Perfinity Integrated Digestion Platform (IDP).
Heating Block System Improves Stability Studies
June 1, 2012 8:33 am | Product Releases | CommentsAsynt has supplied a European Contract Research Organization (CRO) with a custom heating block system to assist chemists analyzing the thermal stability of multiple samples being prepared for its commercial compound libraries.
Integrated LC-DAD System Supports HPLC, UHPLC
June 1, 2012 8:33 am | Product Releases | CommentsAgilent Technologies' 1220 Infinity LC system with DAD brings UHPLC analytical power with diode-array detection to users who do not need the flexibility of a modular system, but still require the highest quality at a low price.
Breaking the 20,000 PSI Barrier
February 7, 2012 5:43 am | Articles | CommentsLC pump engineers have undertaken the formidable task of reaching 20,000 psi and above, rethinking and possibly revolutionizing the pump design.
Vials Certified for High-Sensitivity LCMS MS
December 5, 2011 12:18 pm | Product Releases | CommentsWaters’ TruView LCMS Certified Vials, a line of low-adsorption sample vials, are certified for LCMS/MS analyses where analyte concentrations are on the order of ng/mL or pg/mL and where analytical sensitivity and accuracy are critical.
Web-Based Calculator Simplifies HPLC
December 5, 2011 12:15 pm | Product Releases | CommentsThermo Fisher Scientific provides web-based chromatography assistance to chromatographers looking to optimize methods with the latest column technologies with the HPLC Method Development Calculator.
Flow Meter Ensures High Repeatability
December 5, 2011 12:08 pm | Product Releases | CommentsSensirion’s Nano Flow Sensors for UHPLC applications feature a pressure rating of 1000 bar (15000 psi) and a short response time of 30 msec.
