The February issue of Chromatography Techniques has a plethora of technical articles for any chromatographer or spectroscopy specialist. A large volume splitless injection method is described for the analysis of water with low detection limits, as well as sorbent sampling tips, imaging analysis for HPLC columns, a new FTIR method and much, much more.
FTIR has emerged as a viable alternative to gas chromatography for the qualitative and quantitative analysis of gases. Qualification and quantitation are performed from the wave numbers of the characteristic peaks and peak intensities of the measured gas.
If there was a method for packing material manufacturers to specify shape characteristics and for column manufacturers to inspect incoming materials against those specifications, manufacturing HPLC columns would become more predictable, less costly and exhibit consistent performance. Recent advancements in image analysis could provide the answer.
This article describes a method for the rapid and sensitive detection of 36 CEC analytes in less than 20 minutes per sample. This UHPLC MS/MS method was developed on an Agilent 1290 Infinity LC system coupled to an Agilent 6460 Triple Quadrupole LCMS system using both positive and negative electrospray ionization.
The flexibility to perform separations without pH, temperature or mobile phase restrictions arms chromatographers with powerful tools for tackling tough separations. The right combination of stationary and mobile phase is critical for generating the well-defined, sharp peaks that allow shorter run times.
Sampling using sorbent tubes for analysis by thermal desorption gas chromatography is ideal for a wide range of applications, from monitoring industrial air to odor profiling of foods. However, for those new to the area, the options available can make it difficult to decide how best to proceed.
A multitude of performance factors including dense gas CO2, small particle columns and mass spectrometry with UV detection are speeding up chiral separation methods development. Chirality plays a critical role in drug efficacy because enantiomers may have vastly different biological, pharmacological and toxicological properties.
Waters Corp., Milford, Mass., has published an all-new 212-page Beginner's Guide to Solid Phase Extraction (SPE). The book includes chapters on terms and calculations, methods development, troubleshooting, understanding how liquid chromatography makes SPE powerful, benefits of SPE, an extensive glossary of terms and numerous applications.
Concurrent solvent recondensation–large volume splitless injection meets the EPA’s low detection limits for water analysis, while also reducing sample preparation time by more than one hour. This injection method produces a pressure surge from the vaporizing solvent, forcing the analytes onto the pre-column.
Porvair Sciences’ updated version of its MiniVap Blowdown Evaporator can quickly and safely remove solvent from up to 48 vials in parallel. Made from solvent-resistant black polypropylene, the vial holder has been designed to accommodate up to 48 vials in a standard SLAS/ANSI format.
VICI Valco’s nickel-clad tubing is available with fused silica (FS) tubing, PEEK tubing band polyimide-coated fused silica tubing. These selections make the nickel-clad tubing suited for HPLC and UHPLC use.
An Applications Notebook from JEOL features more than 20 application notes describing the analysis of synthetic polymers, small organic molecules, complex drug mixtures, peptides and proteins using the company’s SpiralTOF MALDI TOF-TOF mass spectrometer. The mass spectrometer’s optics design utilizes a figure-eight ion trajectory to allow a 17-m flight path to fit in a small console.
Agilent Technologies’ 2013 Essential Chromatography and Spectroscopy Catalog is divided into five sections to help the reader easily navigate the company’s growing portfolio, which includes general chromatography, sample preparation, GC and GCMS, LC and LCMS and spectroscopy. This edition of the catalog contains CrossLab products for use with other manufacturers’ instruments. It also includes details about electrochemistry meters and supplies, Captiva syringe filters, Ultra Inert and application-specific GC columns, LC biomolecule and Poroshell 120 columns and OneNeb nebulizer for ICP-OES and MP-AES.
Defiant Technologies’ handheld, portable FROG-4000 Gas Chromatography system operates on batteries and uses ambient air for the carrier gas, allowing for easy and rapid analysis of volatile organic compounds (VOC) in the field in about 5 min. The instrument uses micro-fabricated components to achieve a light weight and robust form factor.
Cerilliant offers Certified Spiking Solutions of nicotine metabolites norcotinine and trans-3-hydroxycotinine, as well as nicotine nitrosamines NNN, NNK and NAB at concentrations of 1.0 mg/mL in methanol for each solution standard. These certified reference solutions can be used as Snap-N-Spike starting materials in the laboratory’s matrix of choice for preparation of calibrators and controls in nicotine testing and other clinical or diagnostic applications by LCMS or GCMS.
ALMSCO International has launched a website focusing on BenchTOF-dx, its time-of-flight mass spectrometer for GC, providing the analytical chemistry community with a valuable online resource. Designed to offer easy navigation, the site enables visitors to gain much faster access to a wealth of information on the company’s products, applications, technical notes, scientific posters and video tutorials.
Agilent Technologies’ OpenLAB Data Store with Lab Applications is an out-of-the-box solution for smaller laboratories that provides secure central storage of the data produced by the proprietary OpenLAB chromatography data systems. The software is designed to streamline the management of laboratory operations, assets and regulatory compliance.
PerkinElmer’s two hyphenated thermal analysis units are designed for the accurate characterization and analysis of inorganic materials, polymers, geological materials and oils. The TL-9000 offers an innovative accessory that enables hyphenation, which facilitates the collection of evolved gases from a thermogravimetric analysis (TGA) or STA and then transfers sequentially to both a FTIR and MS or GCMS.
IonBench’s furniture offerings are dedicated to bringing quiet, vibration-free solutions to mass spectroscopy and liquid chromatography. The MS Bench incorporates a soundproofing solution with anti-vibration features in a solidly-built bench that can reduce system footprint by 30%.
Thermo Fisher Scientific’s Syncronis HPLC columns are available with 3 mm particle size. This particle size complements the existing 1.7 and 5 µm particle sizes.
Protea Biosciences Group’s Amplus wide-pore core shell HPLC columns are a line of liquid chromatography columns specifically designed for intact proteins analysis. This family of HPLC silica-based columns employs core shell technology combined with a specific porosity designed to facilitate proteins separation, including those with high molecular weight.
Isolation Technologies’ new, interactive online tool shows instrument manufacturers and laboratory scientists a broad range of empty column hardware and accessories available from IDEX Health & Science. The interactive brochure as a enables the user to see the most popular in-stock hardware and select by specification.
Fortis Technologies is expanding its current range of liquid chromatography products with the launch of its BIO HPLC and UHPLC Columns. Centered around a 300A silica matrix, the phases are designed specifically for bioanalysis of peptides and proteins, where a larger pore size is required to provide retention and selectivity.
Thermo Fisher Scientific’s Acclaim Trinity Q1 HPLC columns are designed to facilitate high-resolution and high-throughput trace analysis of the herbicides diquat and paraquat in plants by LCMS.
Waters Corp. has published its 2012-2013 Waters Quality Parts, Chromatography Columns and Supplies Catalog.